Son of Scottish actor James McAvoy and British actress Anne-Marie Duff. His father is known for starring in Atonement, The Last King of Scotland and Split.
His parents met when they played on-screen boyfriend and girlfriend on the UK TV series Shameless in 2003.
He was named after his maternal grandfather Brendan Duff.
His father married his mother in 2006. The couple split in 2016. Brendan is his parent's first and only child.
His parents have both acted on the TV series His Dark Materials based on the book by Philip Pullman.
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